Endocrine Abstracts

Introduction: In 1974, the first case of concomitant thyroid and parathyroid disease was reported. Non-medullary thyroid carcinoma has been reported in 6% of patients with Primary hyperparathyroidism. However, the simultaneous occurrence of parathyroid carcinoma along with non-medullary thyroid carcinoma is extremely rare.Case report: We report a case of 60-year-old woman with a history of Diabetes Mellitus type 2 and hypertension. She had no family hist...

Introduction: Gougerot disease is an autoimmune disorder characterized by the lymphoid infiltration of salivary and lachrymal glands leading to the two most common symptoms dry eyes and a dry mouth. Primary hyperparathyroidism (PHPT), one of the most common endocrine disorders, is usually diagnosed by the association of hypercalcemia and parathyroid hormone (PTH) levels that are either elevated or inappropriately normal. The association of PHPT with Gougerot disease is rare, o...

IntroductionHyperthyroidism is a very common disease due to an overactive thyroid gland. Antithyroid drugs (ATD) represent the first line treatement. Their side effects can be severe and even potentially fatal. Among them, agranulocytosis, defined as an absolute neutrophils count less than 500/µl is the most feared one.ObservationWe report the case of 57 year-old woman with no medical history, recently d...

IntroductionThe atypical parathyroid adenoma is a histological diagnosis. It is a parathyroid tumor with atypical histological features different from an adenoma and not similar enough to be considered as a carcinoma.It has an uncertain malignant potential.ObservationWe report the case of a 55 year-old woman, referred to us by her rhumatologist after discovering a severe hypercalcemia when exploring her for o...

BackgroundPrimary hyperparathyroidism (PHPT) results from inappropriate overproduction of parathyroid hormone from one or more of parathyroid glands with consequent hypercalcemia. Medical therapy by bisphosphonates is indicated for patients contraindicated for surgical treatment or those with therapy failure. We report the observation of a patient receiving zoledronic acid for persistent PHPT and who developped bisphosphonate-related osteonecrosis of the...

IntroductionPheochromocytoma is rare neuroendocrine tumor arising from the chromaffin cells of the adrenal medulla. It can be even sporadic or take part of inherited syndromes.ObservationWe report the case of a young 32 year-old woman followed by her oncologist for medullary thyroid cancer treated with surgery and radiotherapy. On the examination of the removed tissue, there was a bilateral cancer, measuring ...

IntroductionAutoimmune polyglandular syndrome (APS) is a rare endocrinopathy, characterized by the coexistence of two or more glandular autoimmune diseases that can appear at different intervals of time.ObservationHerein the case of a young woman descendant of first degree consanguineous marriage, diagnosed since the age of six with celiac disease (CD) where gluten-free diet was not respected due to poor soci...

IntroductionAs hypoglycemia is a common symptom, an organic cause is always the first diagnosis looked for as it can be associated with a specific medical or surgical treatment. Diagnosis of functional etiology isn’t as precise, as the whipple triad can be incomplete. We herein report a serie of confirmed etiology for functional hypoglycemia.MethodsThis is a descriptive retrospective study including 20 c...

IntroductionPrimary amenorrhea should be considered in any patient who has not experienced periodic menstruation by 16 years regardless of the presence of normal growth and development of secondary sexual characteristics.Observation17-year-old patient, who exhibited normal secondary sexual characteristics, normal auxiliary and pubic hairs, normal breast development since the age of 12 with the non-appearance ...

IntroductionGrave’s disease is an autoimmune disease characterized by hyperthyroidism. It is in some cases associated to more autoimmune organs dysfunction. The antithyroid drugs are the first line treatement, and sometimes they are responsible for severe adverse effects.ObservationWe report the case of a 34 year-old man, treated for his grave’s disease with thiamazol for two years. Two weeks after ...